Targeted Therapy Makes Inroads in Medulloblastoma:
نویسندگان
چکیده
منابع مشابه
The rationale for targeted therapies in medulloblastoma.
Medulloblastoma (MB) is the most frequent malignant brain tumor in children. Patients with MB who are classified as having high-risk disease or those with recurrent disease respond poorly to current therapies and have an increased risk of MB-related mortality. Preclinical studies and molecular profiling of MB tumors have revealed upregulation or activation of several key signaling pathways such...
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ژورنال
عنوان ژورنال: Journal of the National Cancer Institute
سال: 2015
ISSN: 0027-8874,1460-2105
DOI: 10.1093/jnci/djv353